Any intelligent fool can make things bigger, more complex, and more violent. It takes a touch of genius - and a lot of courage - to move in the opposite direction.

I believe no woman could have invented calculus.

Anyone who has never made a mistake has never tried anything new.

Any fool can know. The point is to understand.

'Sangamon's Principle,' I said. 'The simpler the molecule, the better the drug. So the best drug is oxygen. Only two atoms. The second-best, nitrous oxide-a me…

Simplicity does not precede complexity, but follows it.

I like a thing simple but it must be simple through complication. Everything must come into your scheme, otherwise you cannot achieve real simplicity.