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17 Francis Crick Quotes

Francis Crick presents clear, confident thoughts on DNA research and the drive behind molecular biology.

Francis Crick quotes

  1. Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.

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  2. Both of us had decided, quite independently of each other, that the central problem in molecular biology was the chemical structure of the gene.

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  3. Biologists must constantly keep in mind that what they see was not designed, but rather evolved. It might be thought, therefore, that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood.

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  4. One of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10,000 years old, in my opinion he should see a psychiatrist.

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  5. We've discovered the secret of life.

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Also attributed

  1. In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.

  2. It is notoriously difficult to define the word living.

  3. The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.

  4. For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.

  5. There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.

  6. Finally one should add that in spite of the great complexity of protein synthesis and in spite of the considerable technical difficulties in synthesizing polynucleotides with defined sequences it is not unreasonable to hope that all these points will be clarified in the near future, and that the genetic code will be completely established on a sound experimental basis within a few years.

  7. Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.

  8. I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.

  9. What could be more foolish than to base one's entire view of life on ideas that, however plausible at the time, now appear to be quite erroneous? And what would be more important than to find our true place in the universe by removing one by one these unfortunate vestiges of earlier beliefs?

  10. If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.

  11. It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.

  12. If revealed religions have revealed anything it is that they are usually wrong.